Problems of regulation

Problems with regulation and the diseases they cause

• salt and Heart disease 
• sugar and Diabetes
• calcium and Osteoporosis
• water and kidney stones
• energy and obesity

The beauty is that moving around fixes this because it forces cells to regulate themselves properly, and on a larger scale, forces the body to manage itself properly.

I added this short article in a rush to build on later, as I wanted to make the point that movement forces our bodies to regulate themselves properly. I was shown much of this clearly in lectures during my degree and found studies to back this up over time, but I have never found the time to elaborate on this and bring the deeper detail.

In How activity and exercise improves your health I do make this point but here I was leaving a reminder to go into the detail and science behind each point to make it clear how the simple act of good regular movement helps and generally prevents major health problems. If a pill did this you would happily pay a huge price but because it comes from free and also because movement is promoted in boring and/or intense ways (depending on how you see it) most people are put off or doing the wrong kinds of movement to get the benefits.

Further reading

• Surreal Video of Stressed Cells Helps Biologists Solve a Decades-Old Mystery. WNK kinases (a type of enzyme) are fluorescent and diffuse throughout the cell. When exposed to a salt solution, they coalesce into larger droplets, looking like the bright green goo in a lava lamp. This process, called “phase separation,” is how the cell knows it needs to bring both water and ions back in, returning to its original state within seconds. Credit: Boyd-Shiwarski, et al., Cell (2022
• Gut Microbes Control the Body’s Thermostat:  In both healthy people and those with life-threatening infections, the gut microbiome appears to help regulate body temperature
• Grape expectations: Dietary grapes promote subtle shifts in human microbiome with potential health implications This research shows that grape consumption alters the taxonomic composition of the microbiome, KEGG pathways, enzyme levels, and metabolic profile.
• Hunter-gatherer lifestyle fosters thriving gut microbiome
  • a team of researchers has sequenced gut microbiomes from Hadza people — members of a hunter-gatherer society in northern Tanzania — and compared them with those from people in Nepal and California¹. The study has found not only that the Hadza tend to have more gut microorganisms than people in the other groups, but that a Western lifestyle seems to diminish the diversity of gut populations.
• Strange Mathematical Pattern Found in The Cells of The Human Body: Relates to Homeostasis, cells and cell regulation.
  • In addition to a total cell count, the study revealed something exciting: when cells are grouped into categories based on their size, each size category contributes roughly the same amount to the body’s mass.  
  • To put it another way, it appears that a natural balancing act is at work, where fewer larger cells and more smaller cells are produced to maintain an even balance between the categories. What’s more, the variation in size in each category was roughly similar as well.
  • My two cents is that everything is related. A larger person requires more of everything, and the body has mechanisms to achieve this balance because interdependency creates the link. Just like adding an extra room to your house means more walls and insulation, and possibly a larger roof. So the balance of infrastructure may stay the same. 
• Dr Adrian Taylor – PA | SB | Psychology | Health Behaviours | Self-regulation
  Physical Activity Researcher Review of current research on Health behaviours
  • Adrian points out that activity is exercise, and diy, family activities are exercise. Just move.
  • Fitter people were 5x less likely to die from COVID-19. 
  • Adrian is the current Editor-in-Chief of Mental Health and Physical Activity 
• Highlights / Dr. Stuart Biddle – PA | SB | Psychology | Behaviour change
  Physical Activity Researcher: Professor of Physical Activity & Health, Dr. Stuart Biddle is affiliated with the University of Southern Queensland, Australia. His main research interest is in health effects, psychology and behavior change related to sedentary behavior and physical activity
• Dr Healy and Goode – SB | Behaviour change | Workplace | Intervention
  Physical Activity Researcher Associate Professor Genevieve Healy and Dr Ana Goode provide us latest research findings from BeUpstanding program of research: a program aiming to support workplaces to stand up, sit less and move more for their health and wellbeing.
• Claudia Teran – PA | Active commute | Behaviour change | Health promotion
  Physical Activity Researcher Claudia Teran Escobar is a Bolivian psychologist. After a bachelor’s degree in Bolivia and a master’s degree in applied and affective psychology in Switzerland, she is now a doctoral student at the University of Grenoble-Alpes. Passionate about Behaviour Change research and its applications for health promotion and the promotion of ecological behaviour, she is part of the multidisciplinary project “MobilAir”.
• Expert Opinion – Sedentary Behaviour | Dunstan | Rebar | Pesola
  Physical Activity Researcher What are the most interesting things in sedentary behaviour research at the moment?
• Professor David Dunstan from the Baker Heart and Diabetes Institute in Melbourne. His research focuses on the role of physical activity and sedentary behaviour in relation to chronic diseases.