Problems of regulation

Problems with regulation and the diseases they cause

• salt and Heart disease 
• sugar and Diabetes
• calcium and Osteoporosis
• water and kidney stones
• energy and obesity

The beauty is that moving around fixes this because it forces cells to regulate themselves properly and on a larger scale forces the body to manage itself properly.

I added this short article in a rush to build on later as I wanted to make the point that movement forces out bodies to regulate themselves properly. I was shown much of this clearly in lectures during my degree and found studies to back this up over time but I have never found the time to elaborate on this and bring the deeper detail.

In How activity and exercise improves your health I do make this point but here I was leaving a reminder to go into the detail and science behind each point to make it clear how the simple act of good regular movement helps and generally prevents major health problems. If a pill did this you would happily pay a huge price but because it comes from free and also because movement is promoted in boring and/or intense ways (depending on how you see it) most people are put off or doing the wrong kinds of movement to get the benefits.

Further reading

• Surreal Video of Stressed Cells Helps Biologists Solve a Decades-Old Mystery. WNK kinases (a type of enzyme) are fluorescent and diffuse throughout the cell. When exposed to a salt solution, they coalesce into larger droplets, looking like the bright green goo in a lava lamp. This process, called “phase separation,” is how the cell knows it needs to bring both water and ions back in, returning to its original state within seconds. Credit: Boyd-Shiwarski, et al., Cell (2022
• Gut Microbes Control the Body’s Thermostat:  In both healthy people and those with life-threatening infections, the gut microbiome appears to help regulate body temperature
• Grape expectations: Dietary grapes promote subtle shifts in human microbiome with potential health implications This research shows that grape consumption alters the taxonomic composition of the microbiome, KEGG pathways, enzyme levels, and metabolic profile.
• Hunter-gatherer lifestyle fosters thriving gut microbiome
  • a team of researchers has sequenced gut microbiomes from Hadza people — members of a hunter-gatherer society in northern Tanzania — and compared them with those from people in Nepal and California¹. The study has found not only that the Hadza tend to have more gut microorganisms than people in the other groups, but that a Western lifestyle seems to diminish the diversity of gut populations.
• Strange Mathematical Pattern Found in The Cells of The Human Body: Relates to Homeostasis, cells and cell regulation.
  • As well as a total cell count, the study revealed something really interesting: if you group cells into categories based on their size, each size category contributes roughly the same amount to the mass of the body.  
  • To put it another way, it appears there’s a natural balancing act going on, where fewer larger cells and more smaller cells are produced to keep the categories even. What’s more, the variation in size in each category was roughly similar as well.
  • My two cents is that everything is related. A bigger person needs more of everything and the body has mechanisms to achieve this balance because the interdependency creates the link. Just like adding an extra room to your house means more walls and insulation and maybe more roof. So the balance of infrastructure may stay the same. 
• Dr Adrian Taylor – PA | SB | Psychology | Health Behaviours | Self-regulation
  Physical Activity Researcher Review of current research on Health behaviours
  • Adrian points out that activity is exercise and diy, family activities are exercise. Just move.
  • Fitter people were 5x less likely to die from covid. 
  • Adrian is the current Editor In chief of mental health and physical activity